Latest News

Clues beginning to emerge on asymtomatic SARS-CoV-2 infection
Back in November of 2020, during the first wave of the COVID-19 pandemic, I was teaching an in-person microbiology laboratory. One of my students had just been home to see his parents, and they all c…
Read more
Could there maybe be better uses of genetics and probiotics?
Professor Meng Dong and his laboratory have created a probiotic that can metabolize alcohol quickly and maybe prevent some of the adverse effects of alcohol consumption. The scientists cloned a highl…
Read more
ChatGPT is not the end of essays in education
The takeover of AI is upon us! AI can now take all our jobs, is the click-bait premise you hear from the news. While I cannot predict the future, I am dubious that AI will play such a dubious role in…
Read more
Fighting infections with infections
Multi-drug-resistant bacterial infections are becoming more of an issue, with 1.2 million people dying of previously treatable bacterial infections. Scientists are frantically searching for new metho…
Read more
A tale of two colleges
COVID-19 at the University of Wisconsin this fall has been pretty much a non-issue. While we are wearing masks, full in-person teaching is happening on campus. Bars, restaurants, and all other busine…
Read more

News

Type 1 Diabetes Vaccine


 

Scientists at Stanford University have created a useable vaccine for Type 1 Diabetes mellitus.  This disease affects many people around the globe by decreasing the amount of insulin produced by the pancreas, causing high blood sugar in patients.  Type 2 diabetes (aka "adult onset" diabetes) is caused by the body's inability to use insulin properly, whereas type 1 diabetes ("juvenile" diabetes) results from the body's inability to produce insulin.  The lack in insulin in type 1 patients has been attributed to the destruction of insulin-producing beta cells in the pancreas by the body's own immune system

Traditionally, autoimmune diseases such as these have been difficult to treat, because it involves manipulating the entire immune system, the body's line of defense against infectious agents and cancer.  The patient's body has developed the unfortunate trait of  fighting against itself in these cases and that is tough to rectify.  This new "vaccine" developed by researchers works in reverse of the normal convention; instead of training the immune system against a virus or bacteria, the vaccine suppresses the part of the immune system that destroys beta cells while leaving the rest of the immune system intact.  This is a promising development not only in the path to curing type 1 diabetes, but also to developing cures for other auto-immune diseases as well.


Sources:

  • http://med.stanford.edu/ism/2013/june/diabetes.html
  • http://www.bbc.co.uk/news/health-23064897
  • http://www.theverge.com/2013/7/1/4482738/type-1-diabetes-reverse-vaccine-forget-about-insulin