News » Chapter 3 Cell Structure and Organization

Biofilm matrix gene expression in B. subtilis

Contributed by microsummer2013 on Aug 15, 2013 - 07:11 PM

In a recent paper that was published by the Gourse Lab at the University of Wisconsin-Madison,discusses the biofilm matrix gene expression in Bacillus subtilis. A biofilm matrix is made up of multicellular communities that stick to many types of surfaces in different environments, and the production of extracellular matrix enables the formation of these communities. Once the biofilm matrix forms, the flagella motility is inhibited by the organism. On a molecular level, the eps and tapA-sipW-tasA are two essential operons that enable the production of the biofilm matrix. In addition to the eps and tapA-sipW-tasA operons, SinR and RemA are two DNA-binding proteins that play vital roles in the regulation as well. The Gourse Lab suggested that the DNA-binding protein SinR negatively regulates the eps operon expression by blocking RemA binding. In addition, SinR functions as an anti-activator to the Peps promoter.

New Insight into Potassium Channels

Contributed by bbialek on Aug 06, 2013 - 09:17 AM

Ion channels are massively important to all cells as they allow for the production of ion gradients as well as important ion movements into the cell. These enzymes work in very complicated and closely regulated ways which were previously unknown. New research has opened up these ion channels and dissected their processes to allow us to more closely describe their actions. 

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