News » Chapter 20 Sexually Transmitted Disease and Those Transmitted by Blood and Body Fluids

Immensely high internal pressure in Herpes virus facilitates DNA ejection from capsid.

Contributed by savsani on Aug 05, 2013 - 09:00 AM

A new study reveals a key mechanism for viral infection that has been highly preserved in viruses that release their genome into the cell nucleus without disassembling the capsid. The study was conducted by Bauer et al at Carnegie Mellon University on the Herpes Virus (HSV-1), one of the most studied viruses with this kind of an infection mechanism. For the first time, it brings into light the presence of high internal pressure of tens of atmospheres due to an extremely condensed genome in a human eukaryotic virus like HSV-1


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